| Date | Time† | Venue | Opponents | Competition | F | A | Att. | ||
| Mon 14-Jul | - | Neutral | Tavernes | Friendly | 8 | 0 | Won | - | [REPORT] |
| Sat 19-Jul | - | Neutral | Denia | Friendly | 4 | 2 | Won | - | [REPORT] |
| Thu 24-Jul | 20:30 | Away | Hercules | Friendly | 1 | 1 | Drew | - | [REPORT] |
| Mon 28-Jul | 19:45 | Away | Norwich City | Friendly | 5 | 1 | Won | 25,243 | [REPORT] |
| Wed 30-Jul | 19:45 | Away | Leyton Orient | Friendly | 5 | 1 | Won | 8,920 | [REPORT] |
| Fri 01-Aug | 17:30 | Neutral | Celtic | Feyenoord Tournament | 2 | 0 | Won | - | [REPORT] |
| Sun 03-Aug | 16:45 | Neutral | Borussia Dortmund | Feyenoord Tournament | 3 | 0 | Won | - | [REPORT] |
| Sun 10-Aug | 15:00 | Home | Roma | Friendly | 5 | 0 | Won | 35,841 | [REPORT] |
| Sat 16-Aug | 15:00 | Away | Middlesbrough | Premier League | 1 | 2 | Lost | 32,623 | [REPORT] |
| Sat 23-Aug | 15:00 | Home | Sunderland | Premier League | 1 | 2 | Lost | 36,064 | [REPORT] |
| Sun 31-Aug | 13:30 | Away | Chelsea | Premier League | 1 | 1 | Drew | 41,790 | [REPORT] |
| Mon 15-Sep | 20:00 | Home | Aston Villa | Premier League | 1 | 2 | Lost | 36,075 | [REPORT] |
| Thu 18-Sep | 19:45 | Home | Wisla Krakow | UEFA Cup | 2 | 1 | Won | 35,751 | [REPORT] |
| Sun 21-Sep | 15:00 | Home | Wigan Athletic | Premier League | 0 | 0 | Drew | 35,808 | [REPORT] |
| Wed 24-Sep | 19:45 | Away | Newcastle United | Carling Cup | 2 | 1 | Won | 20,577 | [REPORT] |
| Sun 28-Sep | 13:30 | Away | Portsmouth | Premier League | 0 | 2 | Lost | 20,352 | [REPORT] |
| Thu 02-Oct | 14:40 | Away | Wisla Krakow | UEFA Cup | 1 | 1 | Drew | 15,000 | [REPORT] |
| Sun 05-Oct | 15:00 | Home | Hull City | Premier League | 0 | 1 | Lost | 36,062 | [REPORT] |
| Sun 19-Oct | 16:00 | Away | Stoke City | Premier League | 1 | 2 | Lost | 27,500 | [REPORT] |
| Thu 23-Oct | 18:10 | Away | Udinese | UEFA Cup | 0 | 2 | Lost | 22,000 | [REPORT] |
| Sun 26-Oct | 15:00 | Home | Bolton Wanderers | Premier League | 2 | 0 | Won | 35,507 | [REPORT] |
| Wed 29-Oct | 20:00 | Away | Arsenal | Premier League | 4 | 4 | Drew | 60,043 | [REPORT] |
| Sat 01-Nov | 17:30 | Home | Liverpool | Premier League | 2 | 1 | Won | 36,183 | [REPORT] |
| Thu 06-Nov | 20:00 | Home | Dinamo Zagreb | UEFA Cup | 4 | 0 | Won | 32,788 | [REPORT] |
| Sun 09-Nov | 15:00 | Away | Manchester City | Premier League | 2 | 1 | Won | 41,893 | [REPORT] |
| Wed 12-Nov | 19:45 | Home | Liverpool | Carling Cup | |||||
| Sat 15-Nov | 15:00 | Away | Fulham | Premier League | |||||
| Sun 23-Nov | 13:30 | Home | Blackburn Rovers | Premier League | |||||
| Thu 27-Nov | 18:00 | Away | NEC Nijmegen | UEFA Cup | |||||
| Sun 30-Nov | 15:00 | Home | Everton | Premier League | |||||
| Tue 02-Dec* | (Quarter-final) | Carling Cup | |||||||
| Mon 08-Dec | 20:00 | Away | West Ham United | Premier League | |||||
| Sat 13-Dec | 15:00 | Home | Manchester United | Premier League | |||||
| Thu 18-Dec | 19:45 | Home | Spartak Moscow | UEFA Cup | |||||
| Sun 21-Dec | 15:00 | Away | Newcastle United | Premier League | |||||
| Fri 26-Dec | 13:00 | Home | Fulham | Premier League | |||||
| Sun 28-Dec | 15:00 | Away | West Bromwich Albion | Premier League | |||||
| Sat 03-Jan* | TBC (3rd round) | FA Cup | |||||||
| Tue 06-Jan* | (Semi-final, 1st leg) | Carling Cup | |||||||
| Sat 10-Jan | 15:00 | Away | Wigan Athletic | Premier League | |||||
| Sat 17-Jan | 15:00 | Home | Portsmouth | Premier League | |||||
| Tue 20-Jan* | (Semi-final, 2nd leg) | Carling Cup | |||||||
| Sat 24-Jan* | (4th round) | FA Cup | |||||||
| Tue 27-Jan | 20:00 | Home | Stoke City | Premier League | |||||
| Sat 31-Jan | 15:00 | Away | Bolton Wanderers | Premier League | |||||
| Sat 07-Feb | 15:00 | Home | Arsenal | Premier League | |||||
| Sat 14-Feb* | (5th round) | FA Cup | |||||||
| Wed 18-Feb* | (Round of 32, 1st leg) | UEFA Cup | |||||||
| Sat 21-Feb | 15:00 | Away | Hull City | Premier League | |||||
| Thu 26-Feb | (Round of 32, 2nd leg) | UEFA Cup | |||||||
| Sat 28-Feb | 15:00 | Away | Sunderland | Premier League | |||||
| Sun 01-Mar | 15:00 | Neutral | (Final) | Carling Cup | |||||
| Tue 03-Mar | 20:00 | Home | Middlesbrough | Premier League | |||||
| Sat 07-Mar* | (Quarter-final) | FA Cup | |||||||
| Thu 12-Mar | (Round of 16, 1st leg) | UEFA Cup | |||||||
| Sat 14-Mar | 15:00 | Away | Aston Villa | Premier League | |||||
| Wed 18-Mar* | (Round of 16, 2nd leg) | UEFA Cup | |||||||
| Sat 21-Mar | 15:00 | Home | Chelsea | Premier League | |||||
| Sat 04-Apr | 15:00 | Away | Blackburn Rovers | Premier League | |||||
| Thu 09-Apr | (Quarter-final, 1st leg) | UEFA Cup | |||||||
| Sat 11-Apr | 15:00 | Home | West Ham United | Premier League | |||||
| Thu 16-Apr | (Quarter-final, 2nd leg) | UEFA Cup | |||||||
| Sat 18-Apr | 15:00 | Home | Newcastle United | Premier League | |||||
| Sat 18-Apr* | Neutral | (Semi-final) | FA Cup | ||||||
| Sat 25-Apr | 15:00 | Away | Manchester United | Premier League | |||||
| Thu 30-Apr | (Semi-final, 1st leg) | UEFA Cup | |||||||
| Sat 02-May | 15:00 | Home | West Bromwich Albion | Premier League | |||||
| Thu 07-May | (Semi-final, 2nd leg) | UEFA Cup | |||||||
| Sat 09-May | 15:00 | Away | Everton | Premier League | |||||
| Sat 16-May | 15:00 | Home | Manchester City | Premier League | |||||
| Wed 20-May | Neutral | (Final) | UEFA Cup | ||||||
| Sun 24-May | 15:00 | Away | Liverpool | Premier League | |||||
| Sat 30-May | 15:00 | Neutral | (Final) | FA Cup |
†UK time
*Cup fixture that may be moved to the following day
